The 1st session will be dedicated to an introduction and an overview of the topic:
Why localize RNA?
Methods – biochemical & imaging (FISH, MS2-like, GFP-mimic RNA aptamers, imaging local translation); large-scale analysis
mRNA localization in yeast & mammals as a platform to study the concepts of mRNA localization & local translation regulation.
mRNA trafficking in model organisms and consequences to physiology
mRNA localization to organelles
Extracellular RNA and implications to cancer research
A list of papers will be distributed on the first lecture. Each student will present one paper from the list. Students are expected to read the papers and participate in the discussion.