Course Identification

Title:

Laboratory animals at the Weizmann Institute of Science

Code:

20193021

Lecturers and Teaching Assistants

Lecturers:

Prof. Alon Harmelin, Dr. Noa Stettner, Dr. Ori Brenner, Dr. Avishag Tuval, Ms. Carmit Bar Natan, Dr. Yuri Kuznetsov, Ms. Sima Peretz, Dr. Gil Hecht

TA's:

N/A

Course Schedule and Location

Year:

2019

Semester:

First Semester

When / Where:

Wednesday, 09:15 - 11:00, WSoS, Rm C

First Lecture:

07/11/2018

Field of Study, Course Type and Credit Points

Life Sciences: Laboratory; Elective; 0.50 points
Life Sciences (Molecular and Cellular Neuroscience Track): Laboratory; Elective; 0.50 points
Life Sciences (Brain Sciences: Systems, Computational and Cognitive Neuroscience Track): Laboratory; Elective; 0.50 points
Life Sciences (Computational and Systems Biology Track): Laboratory; Elective; 0.50 points

Comments

This course is compulsory for those who intend to work with animals. Participants who pass the course will be granted permission to work with laboratory animals. The course includes procedures on animals.

labs will be between 24-27/12 between 13:15-15:30 at the life science student lab. Students will have to participate two of these four dates. Participation is mandatory.

Prerequisites

No

Restrictions

Participants:

65

Language of Instruction

English

Attendance and participation

Obligatory

Grade Type

Pass / Fail

Grade Breakdown (in %)

Final:

100%

Evaluation Type

Examination

Scheduled date 1

Date / due date

02/01/2019

Location

WSoS, Rm C

Time

0900-1100

Remarks

N/A

Scheduled date 2

Date / due date

16/01/2019

Location

Hertzberg, Veterinary resources

Time

0900-1100

Remarks

N/A

Estimated Weekly Independent Workload (in hours)

2

Syllabus

Lecture on ethics: Use of animals in biomedical research, importance of the three 'R's in research, description of the ethical standards in Israel and at the Weizmann Institute.
Lecture on standardization: Environmental and microbiological factors affecting laboratory animals and work with them.
Lecture on rats and mice: History of their biomedical use, their biology, the different strains, anatomic and physiologic differences and their relevance to research.
Lecture on rabbits and hamsters (see 3).
Lecture on fish and Xenopus (see 3).
Lecture on Pain assessment and alleviation, clinical sign assessment, analgesia and euthanasia.
Revision of the theoretical material through a multiple: choice test.
Laboratories: Various methods of handling and holding experimental animals, IP injection, subcutaneous and intravenous injection in fully alert animals, bleeding under anesthesia, tail Sampling, bleeding through artery piercing in the rabbit, Euthanasia. Postmortem lab-learning to dissect and take samples for histologic evaluation. Participation in this part of the course (in its entirety) is compulsory and is a pre-requisite for receiving credit for this course.
Lectures and special procedures on primates:

Learning Outcomes

Upon successful completion of this course students should be able to:

Explain principles in laboratory animals? medicine.
Demonstrate proficiency advanced methodology and experimental approaches in animals' experimentation.
Perform commonly used procedures in different species as well as a postmortem dissection.

Reading List

N/A

Website

N/A