Course Identification

Biology of Cell Death
20193112

Lecturers and Teaching Assistants

Prof. Eli Arama
Dr. Alina Kolpakova

Course Schedule and Location

2019
Second Semester
Tuesday, 09:15 - 11:00, Ebner Auditorium
26/03/2019

Field of Study, Course Type and Credit Points

Life Sciences: Lecture; Elective; Core; 2.50 points
Life Sciences (Molecular and Cellular Neuroscience Track): Lecture; Elective; Core; 2.50 points
Life Sciences (Computational and Systems Biology Track): Lecture; Elective; Core; 2.50 points

Comments

N/A

Prerequisites

No

Restrictions

120

Language of Instruction

English

Attendance and participation

Obligatory

Grade Type

Numerical (out of 100)

Grade Breakdown (in %)

100%

Evaluation Type

Examination

Scheduled date 1

16/07/2019
Ebner Auditorium
0915-1100
N/A

Scheduled date 2

27/08/2019
FGS, Rm C
0900-1100
N/A

Estimated Weekly Independent Workload (in hours)

1

Syllabus

Biology of cell death 2019 (Tuesdays 9:15-11:00/Ebner)

26.3     Genetic regulation of apoptosis – Eli Arama

2.4       BCL-2 protein-regulation of apoptosis – Atan Gross

9.4       Election day

16.4     The extrinsic cell death pathway - apoptosis and necroptosis – David Wallach

23.4     Passover  

30.4     p53 (I) – Moshe Oren

7.5       p53 (II) – Moshe Oren

14.5     The intrinsic cell death pathway, inflammasomes and pyroptosis – David Wallach

21.5     Different forms of cell death: autophagy and necrosis – Adi Kimchi

28.5     System level view of Programmed Cell Death: points of intervention & drug design – Adi Kimchi

4.6       Cellular senescence – Valery Krizhanovsky

11.6     Mitochondria regulation of cell fate – Atan Gross

18.6     Developmental cell death in the nervous system – Avraham Yaron

25.6     No lecture

2.7       Cellular senescence and organismal ageing – Valery Krizhanovsky

9.7       Vital roles of apoptotic caspases – Eli Arama

 

The semester ends in July 12.

Learning Outcomes

Upon successful completion of this course students should be able to:

  1. Apply the knowledge gained in this course to performing research in fields of apoptosis, necrosis, autophagy and senescence.
  2. Develop novel hypotheses and avenues of research related to biology of cell death.
  3. Gain more insight into the process of performing science in academia and require skills for developing into a successful scientist.

Reading List

N/A

Website

N/A