Course Identification
Biology module: Essential cell biology: cytoskeleton, cell adhesion, cell movements
Lecturers and Teaching Assistants
Prof. Alexander Bershadsky, Dr. Sabina Winograd-Katz
Course Schedule and Location
Second Semester
Tuesday, 12:30 - 14:45
11/05/2021
2
Field of Study, Course Type and Credit Points
Science Teaching (non thesis MSc Track): Lecture; Obligatory; Regular; 2.00 points
Prerequisites
Basic knowledge in cell and molecular Biology
Restrictions
For students in the Rothschild-Weizmann program only
Attendance and participation
Estimated Weekly Independent Workload (in hours)
Syllabus
- Methods in cell biology
- Introduction. Cell as a mechanical system
- Actin and actin-related proteins
- Microtubules, associated proteins (MAPs) and organizing centers (MTOCs)
- Intermediate filaments and cytoskeletal linkers. Cytoskeleton and nucleoskeleton
- A multitude of molecular motors
- Cell signaling and cytoskeletal regulation. Small G-proteins
- Cytoskeleton and intracellular traffic
- Cell division
- Cell adhesion to extracellular matrix (ECM) and integrin-dependent signaling
- Cell-cell junctions
- Regulation of cell shape and polarity
- Individual and collective cell migration
- Signal transduction and cancer
Learning Outcomes
Upon successful completion of the course, students should be able to:
- Demonstrate knowledge of various methods in cell biology
- Demonstrate an understanding of the regulation of cellular functions - exemplified by regulation of the cytoskeleton, cell division, and cell motility.
- Demonstrate an understanding of t the interaction between the cell and the environment in health and disease (deregulation of cellular processes in cancer).
Reading List
- ALBERTS, B., JOHNSON, A., LEWIS, J., RAFF, M., ROBERTS, K., & WALTER, P. (2008). Molecular biology of the cell. New York, Garland Science.