Course Identification

Title:

Nucleic acids structure and function

Code:

20232022

Lecturers and Teaching Assistants

Lecturers:

Dr. Shirley Daube

TA's:

N/A

Course Schedule and Location

Year:

2023

Semester:

Second Semester

When / Where:

Thursday, 09:15 - 11:00, WSoS, Rm C

First Lecture:

20/04/2023

End date:

21/07/2023

Field of Study, Course Type and Credit Points

Chemical Sciences: Lecture; Elective; Core; 3.00 points
Life Sciences: Lecture; Elective; Regular; 3.00 points

Comments

(1) The courses that are attended by less than 4 students will be cancelled
(2) Cluster - Bio-related

Prerequisites

Basic Thermodynamics
Basic Reaction Kinetics
Basic Organic chemistry

Restrictions

Participants:

40

Language of Instruction

English

Attendance and participation

Expected and Recommended

Grade Type

Numerical (out of 100)

Grade Breakdown (in %)

Assignments:

70%

Final:

30%

Evaluation Type

Final assignment

Scheduled date 1

Date / due date

N/A

Location

N/A

Time

-

Remarks

N/A

Estimated Weekly Independent Workload (in hours)

3

Syllabus

The discovery of DNA
Physical properties of nucleic acids
Analytical methods for nucleic acids characterization
DNA binding by drugs and proteins
DNA synthesis
DNA transactions: replication; transcription; mutagenesis; repair.
DNA supercoiling and packaging
RNA - structure and function
DNA in nanotechnology and medicine.

Learning Outcomes

Upon successful completion of this course students should be able to:

Recognize and appreciate the structural parameters and chemical properties of nucleic acids and how these affect their biological function.
Know common techniques that are used to characterize, synthesize and purify nucleic acids.
Be able to critically read and review current literature involving chemical and biochemical aspects of nucleic acids.

Reading List

N/A

Website

N/A