Course Identification

Animal Models of CNS Diseases
20243352

Lecturers and Teaching Assistants

Dr. Liora Las, Dr. Noga Zilkha, Dr. Iddo Magen, Dr. Guy Las, Prof. Michal Schwartz , Dr. Avishag Tuval
N/A

Course Schedule and Location

2024
Second Semester
Tuesday, 14:00 - 16:00, WSoS, Rm A
09/04/2024
09/07/2024

Field of Study, Course Type and Credit Points

Life Sciences: 2.00 points
Life Sciences (Brain Sciences: Systems, Computational and Cognitive Neuroscience Track): 2.00 points
Life Sciences (ExCLS Track): Elective; 2.00 points

Comments

Hybrid course

Prerequisites

No

Restrictions

100

Language of Instruction

English

Attendance and participation

Required in at least 80% of the lectures

Grade Type

Pass / Fail

Grade Breakdown (in %)

50%
50%

Evaluation Type

Final assignment

Scheduled date 1

N/A
N/A
-
N/A

Estimated Weekly Independent Workload (in hours)

1

Syllabus

This course provides an in-depth exploration of different animal and cellular models used in the study of Central Nervous System (CNS) diseases. Through lectures and discussions, students will gain a comprehensive understanding of the current state of various neuropathologies. Each lecture will be given by an expert in the field that will focus on a different CNS disease, delving into the pathologies, symptoms, and phenotypes captured by different models. Students will also learn how these models have contributed to uncovering the underlying mechanisms of the diseases. Moreover, we will discuss the strengths and weaknesses of each model, explore the correlation between animal model and human clinical endpoints in different disorders, and examine potential new directions for the field.

Topics to be covered (please note that lectures 2-12 are not necessarily in the correct order):

Lecture 1: Introduction to Animal Models in CNS Research  

Lecture 2: Parkinson's Disease

Lecture 3: Dementia disorders, with a focus on Alzheimer's Disease

Lecture 4: Autism

Lecture 5: Prion diseases

Lecture 6: Amyotrophic Lateral Sclerosis (ALS)

Lecture 7: Addiction and drug addiction

Lecture 8: Huntington's Disease + Aging models

Lecture 9: Depression

Lecture 10: Stress, Anxiety disorders, Post Traumatic Stress Disorder (PTSD) and obsessive-compulsive disorder (OCD)

Lecture 11: Eating disorders

Lecture 12: Autoimmune neurology - Brain Inflammation Model   (Multiple Sclerosis, Stroke)

Lecture 13: Compassion fatigue + Summary

 

 

 

 

 


Learning Outcomes

By the end of this course, students will have gained a profound understanding of various CNS diseases and the corresponding animal models, equipping them to critically evaluate scientific literature and contribute to advancements in the field of neuroscience research

Reading List

Will be provided during course

Website

N/A