Course Identification

Clinical cases in immunology
20243612

Lecturers and Teaching Assistants

Prof. Jakub Abramson
N/A

Course Schedule and Location

2024
Second Semester
N/A
20/06/2024
27/06/2024

Field of Study, Course Type and Credit Points

Life Sciences: Lecture; Elective; Regular; 2.00 points
Life Sciences (Systems Biology Track): 2.00 points

Comments

Students who attended less then 80% of the lectures will not be allowed to take the exam.

20/6 ? Botnar (14:00-17:30)
23/6 ? Benozio Auditorium-191C-all day
24/6 ? Wolfson Auditorium
25/6 ? Class C (FGS) -all day
26/6 ? Wolfson Auditorium at 14:30
27/6 ? Botnar Auditorium-all day

Prerequisites

Students that have never taken a course in immunology (and/or have no immunology background) and plan to take this course should first contact the lecturer.

Restrictions

70

Language of Instruction

English

Attendance and participation

Obligatory

Grade Type

Numerical (out of 100)

Grade Breakdown (in %)

100%

Evaluation Type

Examination

Scheduled date 1

29/07/2024
N/A
0900-1200
N/A

Scheduled date 2

12/08/2024
N/A
1000-1300
N/A

Estimated Weekly Independent Workload (in hours)

2

Syllabus

The aim of this course is to review, deepen and consolidate your knowledge of immunology by presenting and discussing authentic examples of patients suffering from diverse genetically inherited immune disorders. Each lecture will feature a case study of a patient, briefly describing his/her symptoms, clinical examination, medical history, and therapeutic treatments. Based on this information we will try to determine which part of the immune system is dysfunctional and diagnose the specific disease. We will then discuss cellular and molecular mechanisms leading to the specific disorder, as well as possible genetic predisposition. We will then try to compare how much the human phenotype resembles phenotypes in corresponding mouse models. These case studies will be grouped into four major classes of 1)Immunodeficiencies, 2) Autoimmune and inflammatory disorders, 3) Anaphylaxis and Allergy disorders and 4) Lymphoproliferative disorders.

There will be ten to twelve lectures in total; each lecture will cover three to four different, but related, case studies.

 

Thursday June 20

14.15- 15.45 Lecture 1 – Kobi Abramson

16.00- 17.30 Lecture 2 – Kobi Abramson

 

Sunday June 23

14.15- 15.45 Lecture 3 – Kobi Abramson

16.00- 17.30 Lecture 4 – Kobi Abramson

 

Monday June 24

16.00- 17.30 Lecture 5 – Kobi Abramson

 

Tuesday June 25

16.00- 17.30 Lecture 6 – Ronen Alon

 

Wednesday June 26

14.15- 15.45 Lecture 7 - Liran Shlush

16.00- 17.30 Lecture 8  – Kobi Abramson

 

Thursday June 27

14.15- 15.45 Lecture 9 – Kobi Abramson

16.00- 17.30 Lecture 10 – Kobi Abramson

 

 

Learning Outcomes

Upon successful completion of this course students should be able to:

  1. Demonstrate understanding of the amazing complexity of the immune system.
  2. Explain the physiological role and significance of individual immune cell populations in health and disease.
  3. Demonstrate understanding of the pathophysiology of multiple diseases caused by the dysfunction of the immune system.

Reading List

Course textbooks:

  1. Fred Rosen and Raif Geha: Case Studies in Immunology
  2. Helen Chapel et al: Essentials of Clinical Immunology

Website

N/A