Course Identification

Course: Introduction to Neuroscience: Cellular and Synaptic Physiology
Course 20253152: Methods in Neuroscience Theoretical 

This lab course will take place in early September 2025. It will include extensive hands-on experiments in three labs, followed by data analysis and submission of written reports. The main emphasis will be given to techniques of neurophysiology, neural activity imaging, and human brain imaging. Techniques covered in the lab course will include, for example:

1. Extracellular and intracellular recordings in vivo.
2. Fiber photometry of neural activity/neuromodulatory release in behaving animals
3. Quantifying gene expression using molecular biology methods.
4. Optogenetics.
5. In vivo voltage imaging in a small model animal.
6. In vivo calcium imaging in freely moving mice.
7. MRI imaging of inanimate samples and human volunteers.

The number of participants is not limited, and each student is required to rotate and submit reports in 3 labs.

Upon successful completion of this course, students should be able to:

Demonstrate knowledge in a wide range of neuroscience methods.
Read and understand research papers that utilize modern molecular approaches, neurophysiology, and imaging techniques.
Conduct experiments and analyze data using electrophysiology, optical imaging and fMRI

The Axon Guide (3rd edition) - available online from various sources.
Imaging in Neuroscience - a Laboratory Manual (Cold Spring Harbor Press)