Course Identification

Protein Structure and Function 1
20252131

Lecturers and Teaching Assistants

Prof. Deborah Fass, Dr. Shifra Lansky
Ariel Tennenhouse

Course Schedule and Location

2025
First Semester
Tuesday, 09:15 - 11:00, Wolfson Auditorium

Tutorials
Sunday, 10:15 - 11:00, Belfer, Botnar Auditorium
05/11/2024
28/01/2025

Field of Study, Course Type and Credit Points

Chemical Sciences: Lecture; Core; 3.00 points
Life Sciences: Lecture; 3.00 points

Comments

Tutorials will be on Sundays 1015-1100 at Belfer, Botnar Auditorium

The tutorial will be held for one time only on Wednesday, November 13 1415-1500 at WSoS, Rm C

Prerequisites

No

Restrictions

200

Language of Instruction

English

Attendance and participation

Obligatory

Grade Type

Numerical (out of 100)

Grade Breakdown (in %)

50%
50%

Evaluation Type

Examination

Scheduled date 1

04/02/2025
WSoS, Rm C,WSoS, Rm B
0900-1200
N/A

Scheduled date 2

20/03/2025
WSoS, Rm 5
0900-1200
N/A

Estimated Weekly Independent Workload (in hours)

4

Syllabus

Protein Structure and Function I (PSF I) 2024-2025 Syllabus
 

Lecture 1 (5/11/24) SL

Exploring the protein universe

Lecture 2 (12/11/24) DF

Protein primary structure: the exquisite physical-chemical composition of proteins

Lecture 3 (19/11/24) DF

Protein secondary structure: helices, sheets, and beyond!

Lecture 4 (26/11/24) SL

Protein tertiary structure: folds, evolution, and structure determination

Lecture 5 (3/12/24) DF

Protein quaternary structure and the building of complex functions

Lecture 6 (10/12/24) DF

Protein thermodynamics: driving forces and energy landscapes

Lecture 7 (17/12/24) SL

Protein-protein interactions and protein regulation

Lecture 8 (24/12/24) SL

Proteins in motion: computational and experimental methods for studying protein dynamics

Lecture 9 (31/12/24) DF

Enzymes

Lecture 10 (7/1/25) SL

Membrane proteins

Lecture 11 (14/1/24) DF

Molecular machines and chaperones

Lecture 12 (21/1/24) SL

Protein design and engineering

Lecture 13 (28/1/24) DF

Proteins in disease: molecular mechanisms, drugs, and drug design

Learning Outcomes

Upon successful completion of this course students should be able to understand why proteins fold and be familiar with the factors influencing protein folding, interaction, and function. They should be able to critically evaluate contemporary literature reporting data and analysis of protein structure determination. They should be inspired to carry out research in the fields of protein biochemistry and structural biology!

Reading List

N/A

Website

N/A