WEIZMANN
SCHOOL OF SCIENCE
APEX_PUBLIC_USER
Course Identification
Title:
Nucleic acids structure and function
Code:
20252171
Lecturers and Teaching Assistants
Lecturers:
Dr. Shirley Daube
TA's:
Atar Gilat
Course Schedule and Location
Year:
2025
Semester:
First Semester
When / Where:
Thursday, 09:15 - 11:00, WSoS, Rm C
Tutorials
Monday, 11:00 - 12:00, WSoS, Rm B
First Lecture:
04/11/2024
End date:
30/01/2025
Field of Study, Course Type and Credit Points
Chemical Sciences: Lecture; Elective; Core; 3.00 points
Life Sciences: Lecture; 3.00 points
Comments
(1) The courses that are attended by less than 4 students will be cancelled
(2) Cluster - Bio-related
This week's tutorial will be on Wednesday, January 8 between 12-13 at WSoS Room B.
Prerequisites
Basic Thermodynamics
Basic Reaction Kinetics
Basic Organic chemistry
Restrictions
Participants:
25
Language of Instruction
English
Attendance and participation
Expected and Recommended
Grade Type
Numerical (out of 100)
Grade Breakdown (in %)
Assignments:
70%
Final:
30%
Evaluation Type
Final assignment
Scheduled date 1
Date / due date
N/A
Location
N/A
Time
-
Remarks
N/A
Estimated Weekly Independent Workload (in hours)
3
Syllabus
The discovery of DNA
Physical properties of nucleic acids
Analytical methods for nucleic acids characterization
DNA binding by drugs and proteins
DNA synthesis
DNA transactions: replication; transcription; mutagenesis; repair.
DNA supercoiling and packaging
RNA - structure and function
DNA in nanotechnology and medicine.
Learning Outcomes
Upon successful completion of this course students should be able to:
Recognize and appreciate the structural parameters and chemical properties of nucleic acids and how these affect their biological function.
Know common techniques that are used to characterize, synthesize and purify nucleic acids.
Be able to critically read and review current literature involving chemical and biochemical aspects of nucleic acids.
Reading List
N/A
Website
N/A
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