Course Identification

Nucleic acids structure and function
20252171

Lecturers and Teaching Assistants

Dr. Shirley Daube
Atar Gilat

Course Schedule and Location

2025
First Semester
Thursday, 09:15 - 11:00, WSoS, Rm C

Tutorials
Monday, 11:00 - 12:00, WSoS, Rm B
04/11/2024
30/01/2025

Field of Study, Course Type and Credit Points

Chemical Sciences: Lecture; Elective; Core; 3.00 points
Life Sciences: Lecture; 3.00 points

Comments

(1) The courses that are attended by less than 4 students will be cancelled
(2) Cluster - Bio-related

This week's tutorial will be on Wednesday, January 8 between 12-13 at WSoS Room B.

Prerequisites

  • Basic Thermodynamics
  • Basic Reaction Kinetics
  • Basic Organic chemistry

Restrictions

25

Language of Instruction

English

Attendance and participation

Expected and Recommended

Grade Type

Numerical (out of 100)

Grade Breakdown (in %)

70%
30%

Evaluation Type

Final assignment

Scheduled date 1

N/A
N/A
-
N/A

Estimated Weekly Independent Workload (in hours)

3

Syllabus

  • The discovery of DNA
  • Physical properties of nucleic acids
  • Analytical methods for nucleic acids characterization
  • DNA binding by drugs and proteins
  • DNA synthesis
  • DNA transactions: replication; transcription; mutagenesis; repair.
  • DNA supercoiling and packaging
  • RNA - structure and function
  • DNA in nanotechnology and medicine.

Learning Outcomes

Upon successful completion of this course students should be able to:

  1. Recognize and appreciate the structural parameters and chemical properties of nucleic acids and how these affect their biological function.
  2. Know common techniques that are used to characterize, synthesize and purify nucleic acids.
  3. Be able to critically read and review current literature involving chemical and biochemical aspects of nucleic acids.

Reading List

N/A

Website

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