The goal of this course is to review, deepen, and solidify your understanding of immunopathology and clinical immunology through the presentation and analysis of authentic cases involving patients with rare disorders of the immune system.
Each lecture will focus on a specific group of immune disorders with similar phenotype. Each lecture will be presented in a Dr. House style including patient’s symptoms, clinical findings, medical history, and therapeutic interventions. Using this information, we will work through the diagnostic process, identifying which components of the immune system are impaired and determining the likely diagnosis.
Following diagnosis, we will explore the cellular and molecular mechanisms underlying the disorder, as well as any known genetic predispositions. We will also compare the clinical presentation in humans to corresponding phenotypes in mouse models, where available.
The case studies are centered around four major categories:
- Primary Immunodeficiencies
- Autoimmune Disorders
- Allergic and Anaphylactic Reactions
- Lymphoproliferative Diseases
This case-based approach is designed to bridge clinical observation with mechanistic insight, providing a comprehensive understanding of how immune system dysfunction manifests in patients.