Course Identification

Core Immunology - Cells and Molecules
20263291

Lecturers and Teaching Assistants

Prof. Jakub Abramson, Prof. Steffen Jung, Prof. Ziv Shulman, Dr. Ranit Kedmi, Prof. Noam Stern-Ginossar, Dr. Moshe Biton
N/A

Course Schedule and Location

2026
First Semester
Wednesday, 09:15 - 11:00, Benoziyo Biochemistry Auditorium 191
29/10/2025
21/01/2026

Field of Study, Course Type and Credit Points

Life Sciences: Lecture; 2.50 points
Life Sciences (ExCLS Track): 2.50 points

Comments

The course will be held for one time only on Thursday, November 20, 2025 (instead of Wednesday, November 19) at Benoziyo Biochemistry auditorium 191c. Hours remain the same.

Prerequisites

No

Restrictions

200

Language of Instruction

English

Attendance and participation

Expected and Recommended

Grade Type

Numerical (out of 100)

Grade Breakdown (in %)

100%

Evaluation Type

Examination

Scheduled date 1

N/A
N/A
-
N/A

Scheduled date 2

N/A
N/A
-
N/A

Estimated Weekly Independent Workload (in hours)

3

Syllabus

 

1

 

History of Immunology

JA

2

 

Introduction to the immune system

JA

3

 

Innate Immune cells  - cellular players  NK, ILC, DC, macrophages, granulocytes

SJ

4

 

Innate effector mechanisms TLR, NLR, CLR, complement, phagocytosis, inflammation

SJ

5

 

Adaptive Immunity - Antigen processing & presentation on MHCI/II

RK

6

 

Adaptive Immunity - T cells 1 :  T cell  development and selection in the thymus; tolerance

JA

7

 

Adaptive Immunity - T cells 2: Peripheral T cell responses and functions

RK

8

 

Adaptive immunity - B cells and antibodies 1 (Immunoglobulin locus, recombination, somatic hypermutation, etc)

ZS

9

 

Adaptive immunity - B cells and antibodies 2 (B cell development, maturation and function, therapeutic antibodies

ZS

10

 

Mucosal & epithelial barrier immunity – immune response at mucosal surfaces (lungs, intestine) and other epithelial barriers (skin) – crosstalk between immune cells and epithelial cells, types of epithelial cells; common defense mechanisms (defensins, mucins, tight junctions, AMPs, PRRs, IgA); role of microbiome + metabolites on immune system;  resident memory; MALT, GALT, IELs; mucosal vaccines

MB

11

 

Immunity to Infection  (anti-viral immunity as a paradigm)

NSG

12

 

Immune Disorders (immunodeficiencies, autoimmunity, autoinflammation, allergies,…)

JA

 

 

 

 

Learning Outcomes

By the end of this course, students will have a solid foundational understanding of the cellular and molecular mechanisms of the immune system. They will be able to describe the roles of innate and adaptive immunity, explain key processes such as antigen recognition, immune cell development, and immune responses to pathogens, and apply core immunological concepts to experimental and clinical contexts

Reading List

Janeway's IMMUNOBIOLOGY, by Murphy and Weaver 

Garland Science; 9th or 10th  edition , available in the WIS library

Website

N/A