1
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History of Immunology
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JA
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2
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Introduction to the immune system
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JA
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3
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Innate Immune cells - cellular players NK, ILC, DC, macrophages, granulocytes
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SJ
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4
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Innate effector mechanisms TLR, NLR, CLR, complement, phagocytosis, inflammation
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SJ
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5
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Adaptive Immunity - Antigen processing & presentation on MHCI/II
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RK
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6
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Adaptive Immunity - T cells 1 : T cell development and selection in the thymus; tolerance
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JA
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7
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Adaptive Immunity - T cells 2: Peripheral T cell responses and functions
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RK
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8
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Adaptive immunity - B cells and antibodies 1 (Immunoglobulin locus, recombination, somatic hypermutation, etc)
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ZS
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9
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Adaptive immunity - B cells and antibodies 2 (B cell development, maturation and function, therapeutic antibodies
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ZS
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10
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Mucosal & epithelial barrier immunity – immune response at mucosal surfaces (lungs, intestine) and other epithelial barriers (skin) – crosstalk between immune cells and epithelial cells, types of epithelial cells; common defense mechanisms (defensins, mucins, tight junctions, AMPs, PRRs, IgA); role of microbiome + metabolites on immune system; resident memory; MALT, GALT, IELs; mucosal vaccines
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MB
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11
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Immunity to Infection (anti-viral immunity as a paradigm)
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NSG
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12
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Immune Disorders (immunodeficiencies, autoimmunity, autoinflammation, allergies,…)
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JA
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