Course Identification

Signal Transduction
20263482

Lecturers and Teaching Assistants

Prof. Rony Seger, Prof. David Wallach, Prof. Yosef Yarden, Prof. Ami Navon
N/A

Course Schedule and Location

2026
Second Semester
Wednesday, 11:15 - 13:00, WSoS, Rm C
15/04/2026
01/07/2026

Field of Study, Course Type and Credit Points

Life Sciences: Lecture; Core; 2.00 points
Life Sciences (Systems Biology Track): Lecture; 2.00 points
Life Sciences (Brain Sciences: Systems, Computational and Cognitive Neuroscience Track): Lecture; 2.00 points

Comments

The course will be held for one time only on Tuesday, 26/5 between 9:15-11:00 at WSoS Room C

Prerequisites

No

Restrictions

No

Language of Instruction

English

Attendance and participation

Required in at least 80% of the lectures

Grade Type

Numerical (out of 100)

Grade Breakdown (in %)

100%

Evaluation Type

Examination

Scheduled date 1

12/07/2026
WSoS, Rm 1,WSoS, Rm 2
0900-1200
N/A

Scheduled date 2

05/08/2026
WSoS, Rm 1
0900-1200
N/A

Estimated Weekly Independent Workload (in hours)

2

Syllabus

1) Introduction/PKA signaling 
2) Protein kinases and phosphatases
3) Ligands, adaptors and G protein coupled receptors
4) T-cell, B-Cell, Olfactory, and other receptors
5) Receptor Tyr Kinases
6) Coordination of immune defense by TNF superfamily signaling
7) Intracellular signaling the ERK cascade
8) Intracellular signaling p38/JNK/ERK5 cascades
9)  Intracellular signaling - PKC, AKT, Calcium 
10) Cancer signaling
11) Signaling inhibitors as therapeutic agents
12) Summary, preparation for exam 

Learning Outcomes

Upon successful completion of this course students should be  able to:

[1] Demonstrate proficiency in cutting edge studies in the field.

[2] Cope with current questions in the field of signal transduction.

Reading List

Biochemistry of Signal Transduction and Regulation by Gerhard Krauss, Wiley-VCH fourth addition.

https://www.science.org/journal/signaling

http://stke.sciencemag.org/index.dtl

Website

N/A