Course Identification

Title:

Signal Transduction

Code:

20263482

Lecturers and Teaching Assistants

Lecturers:

Prof. Rony Seger

TA's:

N/A

Course Schedule and Location

Year:

2026

Semester:

Second Semester

When / Where:

Wednesday, 11:15 - 13:00, WSoS, Rm C

First Lecture:

18/03/2026

End date:

24/06/2026

Field of Study, Course Type and Credit Points

Life Sciences: Lecture; Core; 2.00 points
Life Sciences (Systems Biology Track): Lecture; 2.00 points
Life Sciences (Brain Sciences: Systems, Computational and Cognitive Neuroscience Track): Lecture; 2.00 points

Comments

N/A

Prerequisites

No

Restrictions

Participants:

No

Language of Instruction

English

Attendance and participation

Required in at least 80% of the lectures

Grade Type

Numerical (out of 100)

Grade Breakdown (in %)

Final:

100%

Evaluation Type

Examination

Scheduled date 1

Date / due date

N/A

Location

N/A

Time

-

Remarks

N/A

Scheduled date 2

Date / due date

N/A

Location

N/A

Time

-

Remarks

N/A

Estimated Weekly Independent Workload (in hours)

2

Syllabus

1) Introduction/PKA signaling
2) Ligands and RTKs
3) Adaptors and Interaction domains
4) GPCRs
5) Intracellular signaling (ERK)
6) Intracellular signaling (JNK, p38, AKT)
7) Intracellular signaling (Kinases and calcium signaling)
8) Phosphatases
9) Signaling in Development
10) Signaling in Immune defence
11) Localization of intracellular signaling
12) Signaling networks in disease
13) Signaling inhibitors as therapeutic agents for cancer and other diseases.
14) Summary, preparation for exam

Learning Outcomes

Upon successful completion of this course students should be be able to:

[1] Demonstrate proficiency in cutting edge studies in the field.

[2] Cope with current questions in the field of signal transduction.

Reading List

Biochemistry of Signal Transduction and Regulation by Gerhard Krauss, Wiley-VCH fourth addition.

http://www.signaling-gateway.org

http://stke.sciencemag.org/index.dtl

Website

N/A