Course Identification

Biology module: Essential cell biology: cytoskeleton, cell adhesion, cell movements
20196072

Lecturers and Teaching Assistants

Prof. Alexander Bershadsky, Dr. Sabina Winograd-Katz
N/A

Course Schedule and Location

2019
Second Semester
Tuesday, 09:00 - 10:30, San Martin
Thursday, 09:00 - 10:30, San Martin
04/06/2019
11/07/2019
2

Field of Study, Course Type and Credit Points

Science Teaching (non thesis MSc Track): Lecture; Obligatory; 2.00 points

Comments

לתלמידי שני השנתונים

Prerequisites

Basic knowledge in cell and molecular Biology

Restrictions

20
For students in the Rothschild-Weizmann program only

Language of Instruction

Hebrew

Attendance and participation

Obligatory

Grade Type

Numerical (out of 100)

Grade Breakdown (in %)

30%
70%

Evaluation Type

Examination

Scheduled date 1

23/07/2019
FGS, Rm B
1000-1200
N/A

Scheduled date 2

13/08/2019
FGS, Rm A
1000-1200
N/A

Estimated Weekly Independent Workload (in hours)

2

Syllabus

  • Methods in cell biology
  • Introduction. Cell as a mechanical system
  • Actin and actin-related proteins
  • Microtubules, associated proteins (MAPs) and organizing centers (MTOCs)
  • Intermediate filaments and cytoskeletal linkers. Cytoskeleton and nucleoskeleton
  • A multitude of molecular motors
  • Cell signaling and cytoskeletal regulation. Small G-proteins
  • Cytoskeleton and intracellular traffic
  • Cell division
  • Cell adhesion to extracellular matrix (ECM) and integrin-dependent signaling
  • Cell-cell junctions
  • Regulation of cell shape and polarity
  • Individual and collective cell migration
  • Signal transduction and cancer

Learning Outcomes

Upon successful completion of the course, students should be able to:

  1. Demonstrate knowledge of various methods in cell biology
  2. Demonstrate an understanding of the regulation of cellular functions - exemplified by regulation of the cytoskeleton, cell division, and cell motility.
  3. Demonstrate an understanding of t the interaction between the cell and the environment in health and disease (deregulation of cellular processes in cancer).

Reading List

  • ALBERTS, B., JOHNSON, A., LEWIS, J., RAFF, M., ROBERTS, K., & WALTER, P. (2008). Molecular biology of the cell. New York, Garland Science.

Website

N/A