The Drug Discovery unit is a part of Israel Nation Center of Personal Medicine (INCPM). Our facility is a unique one in Israel and serves as a “bridge” between academic research and pharmaceutical industry.
During the course, students will learn about principles, methods and goals of Drug Discovery and High Throughput Screening. Terminology and experimental “know how” will be discussed: theory, approaches, experimental pipeline etc. Students will practically perform different types of the experiments demonstrating HTS methods. We will perform in the lab both enzymatic and cell-based experiments. The lab work will be done in 384-well plates using automated instrumentation. To detect the experimental results we will use different plate readers and imaging gear in our HTS lab. The students will learn about data collection, data analysis and statistical considerations. The course includes a guided tour at the INCPM for demonstration of robotic systems and completely automated workflow.