Course Identification

Title:

Biology of Cell Death

Code:

20233202

Lecturers and Teaching Assistants

Lecturers:

Prof. Eli Arama, Prof. Adi Kimchi, Prof. Moshe Oren, Prof. David Wallach, Prof. Atan Gross, Prof. Valery Krizhanovsky, Prof. Avraham Yaron

TA's:

N/A

Course Schedule and Location

Year:

2023

Semester:

Second Semester

When / Where:

Tuesday, 09:15 - 11:00, FGS, Rm C

First Lecture:

18/04/2023

End date:

21/07/2023

Field of Study, Course Type and Credit Points

Life Sciences: Lecture; Elective; Regular; 2.50 points

Comments

Make-up lecture: April 27th , 16:15-18:00 , FGS room C

Prerequisites

No

Restrictions

Participants:

120

Language of Instruction

English

Attendance and participation

Expected and Recommended

Grade Type

Numerical (out of 100)

Grade Breakdown (in %)

Final:

100%

Evaluation Type

Examination

Scheduled date 1

Date / due date

01/08/2023

Location

FGS, Rm C

Time

0900-1100

Remarks

N/A

Scheduled date 2

Date / due date

29/08/2023

Location

FGS, Rm C

Time

0900-1100

Remarks

N/A

Estimated Weekly Independent Workload (in hours)

1

Syllabus

Semester 2 (16/04/2023-21/07/2023)

Biology of cell death 2023 (Tuesdays 9:15-11:00)

18.4 Genetic regulation of programmed cell death – Eli Arama

25.4 Memorial day

2.5 The extrinsic cell death pathway - apoptosis and necroptosis – David Wallach

9.5 Apoptosis - a historical and personal perspective – Gerry Cohen

16.5 The intrinsic cell death pathway, inflammasomes and pyroptosis – David Wallach

23.5 p53 (I) – Moshe Oren

30.5 BCL-2 protein-regulation of apoptosis – Atan Gross

6.6 p53 (II) – Moshe Oren

13.6 Autophagy (I) – Adi Kimchi

20.6 Autophagy (II) and the interface with programmed cell death and human diseases – Adi Kimchi

27.6 Mitochondria regulation of cell fate – Atan Gross

4.7 Cellular senescence – Valery Krizhanovsky

11.7 Developmental cell death in the nervous system – Avraham Yaron

18.7 Caspase-dependent non-lethal cellular processes (CDPs) – Eli Arama

The semester ends on July 21

Exam Schedule A - 1.8.23 (tentative)

Exam Schedule B - 29.8.23 (tentative)

Learning Outcomes

Upon successful completion of this course students should be able to:

Apply the knowledge gained in this course to performing research in fields of apoptosis, necrosis, pyroptosis, feroptosis, parthanatos, autophagy, senescence, and non-lethal functions of apoptotic proteins.
Develop novel hypotheses and avenues of research related to biology of cell death.
Gain more insight into the process of performing science in academia and require skills for developing into a successful scientist.

Reading List

N/A

Website

N/A