Course Identification

Lecture 1 (24/10/23) DF
Course Introduction

Protein primary structure: physical-chemical composition of proteins

31/10/23

No class—Israeli municipal elections

Lecture 2 (7/11/23) DF
Protein secondary structure: helices, sheets, and beyond!
 

Lecture 3 (14/11/23) RD
Tertiary structure: folding motifs, topology, evolution of protein folds

Lecture 4 (21/11/23) RD
Principles, practices, challenges, and recent revolutions in protein structure determination

Lecture 5 (28/11/23) RD
Protein structure determination (continued), computational protein fold prediction

Lecture 6 (5/12/23) DF
Quaternary structure: protein oligomerization

Lecture 7 (12/12/23) DF

Quaternary structure: polymerization and protein pathologies

Lecture 8 (19/12/23) DF
Protein thermodynamics

Lecture 9 (26/12/23) RD
Protein-protein interactions

Lecture 10 (2/1/24) DF
Protein folding, conformational changes, and dynamics in protein function

Lecture 11 (9/1/24) RD

Enzymes

Lecture 12 (16/1/24) DF
Membrane proteins

Lecture 13 (23/1/24) RD
Molecular Machines

Upon successful completion of this course students should be able to understand why proteins fold and be familiar with the factors influencing protein folding, interaction, and function. They should be able to critically evaluate contemporary literature reporting data and analysis of protein structure determination. They should be inspired to carry out research in the fields of protein biochemistry and structural biology!