At its core, neuroscience is the endeavor of understanding the link between particular brain states and behavior. Studying humans has the advantage of allowing us to measure not only overt behavior, but also gives us access to the internal states and experiences of our subjects. We can therefore study much richer, more complex behaviors. This course will cover some of the fundamental approaches in human neuroscience: behavioral and cognitive neuroscience, computational approaches, neuroimaging and other neural recording techniques in humans. This will be done through examining a wide range of topics, from low-level vision to complex cognitive skill such as memory and learning. Focusing on the link between brain and behavior, we will discuss the organization of the brain into networks, plasticity, individual differences, and what goes wrong in neurological and psychiatric disease.